In the movie: Cujo, a friendly St. Bernard, contracts rabies and conducts a reign of terror on a small American town. In real life: Man’s best friend suddenly turning into a vicious enemy is indeed the stuff of nightmares. We can protect our companion Dogs from contracting the deadly virus by getting them vaccinated. Likewise, we can protect ourselves by getting pre-exposure shots, especially if we hang around animals all the time (in case you work in animal care or you rescue animals). Human companions should also supervise their Dogs at all times to keep them from getting into dangerous situations.